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Total 66 results found since Jan 2013.
Patient Report on the Impact of Coronavirus Disease 2019 and Living With Lung Cancer
CONCLUSIONS: An integrative patient-reported view on the impact of COVID-19 is important for adequate preparation to ensure undisrupted treatment and allocation of resources.PMID:37663676 | PMC:PMC10472288 | DOI:10.1016/j.jtocrr.2023.100549
Source: Clinical Lung Cancer - September 4, 2023 Category: Cancer & Oncology Authors: Tendai M Chihuri Upal Basu Roy Amy Moore Anne-Marie Baird Tracey L Grant Bellinda L King-Kallimanis Source Type: research
Building a Digital Immune System
Credit: Courtesy of Dr. Tomas Helikar.
The power of computer code has been a longtime fascination for Tomas Helikar, Ph.D., a professor of biochemistry at the University of Nebraska-Lincoln (UNL). In college, when he learned he could use that power to help researchers better understand biology and improve human health, Dr. Helikar knew he’d found his ideal career. Since then, he’s built a successful team of scientists studying the ways we can use mathematical models in biomedical research, such as creating a digital replica of the immune system that could predict how a patient will react to infectious microorganisms ...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - June 28, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Cells Tools and Techniques Bioinformatics Computational Biology Cool Tools/Techniques Modeling Profiles Source Type: blogs
Fight Aging! Newsletter, June 26th 2023
This study explored the association between different cooking fuel types and the risk of cancer and all-cause mortality among seniors constructing Cox regression models. Data were obtained by linking waves of 6, 7, and 8 of the Chinese Longitudinal Healthy Longevity Survey, which included a total of 7,269 participants who were 65 years old and over. Cooking fuels were categorized as either biomass, fossil, or clean fuels. And the effects of switching cooking fuels on death risk were also investigated using Cox regression models.
The results indicate that, compared with the users of clean fuels, individuals using bio...
Source: Fight Aging! - June 25, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, June 19th 2023
In conclusion, among Swedish middle-aged subjects, nearly two-thirds showed complete fatty degeneration of thymus on CT.
Age-Related Dysfunction of Water Homeostasis
https://www.fightaging.org/archives/2023/06/age-related-dysfunction-of-water-homeostasis/
Dehydration can be an issue in older people. As in every complex system in the body, the mechanisms by which hydration is regulated become dysfunctional with advancing age. Researchers here look at the brain region responsible for regulating some of the response to dehydration, cataloging altered gene expression in search of the more important mechani...
Source: Fight Aging! - June 18, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Primary role of type I interferons for the induction of functionally optimal antigen-specific CD8 < sup > + < /sup > T cells in HIV infection
EBioMedicine. 2023 Apr 12;91:104557. doi: 10.1016/j.ebiom.2023.104557. Online ahead of print.ABSTRACTBACKGROUND: CD8+ T cells equipped with a full arsenal of antiviral effector functions are critical for effective immune control of HIV-1. It has nonetheless remained unclear how best to elicit such potent cellular immune responses in the context of immunotherapy or vaccination. HIV-2 has been associated with milder disease manifestations and more commonly elicits functionally replete virus-specific CD8+ T cell responses compared with HIV-1. We aimed to learn from this immunological dichotomy and to develop informed strategi...
Source: Cancer Control - April 14, 2023 Category: Cancer & Oncology Authors: Mariela P Cabral-Piccin Laura Papagno Xavier Lahaye Federico Perdomo-Celis Stevenn Volant Eoghann White Val érie Monceaux Sian Llewellyn-Lacey R émi Fromentin David A Price Nicolas Chomont Nicolas Manel Asier Saez-Cirion Victor Appay Source Type: research
Breakthrough SARS-CoV-2 infections among patients with cancer following two and three doses of COVID-19 mRNA vaccines: a retrospective observational study from the COVID-19 and Cancer Consortium
This study was partly supported by grants from the National Cancer Institute grant number P30 CA068485 to C-YH, YS, SM, JLW; T32-CA236621 and P30-CA046592 to C.R.F; CTSA 2UL1TR001425-05A1 to TMW-D; ACS/FHI Real-World Data Impact Award, P50 MD017341-01, R21 CA242044-01A1, Susan G. Komen Leadership Grant Hunt to MKA. REDCap is developed and supported by Vanderbilt Institute for Clinical and Translational Research grant support (UL1 TR000445 from NCATS/NIH).PMID:36818595 | PMC:PMC9925160 | DOI:10.1016/j.lana.2023.100445
Source: Cancer Control - February 23, 2023 Category: Cancer & Oncology Authors: Toni K Choueiri Chris Labaki Ziad Bakouny Chih-Yuan Hsu Andrew L Schmidt Gilberto de Lima Lopes Clara Hwang Sunny R K Singh Chinmay Jani Lisa B Weissmann Elizabeth A Griffiths Susan Halabi Ulysses Wu Stephanie Berg Timothy E O'Connor Trisha M Wise-Draper Source Type: research
Persistent disparities of cervical cancer among American Indians/Alaska natives: Are we maximizing prevention tools?
Gynecol Oncol. 2022 Nov 15;168:56-61. doi: 10.1016/j.ygyno.2022.11.007. Online ahead of print.ABSTRACTBACKGROUND: Cervical cancer incidence and mortality disparities experienced by American Indian/Alaska Native (AI/AN) women have persisted for decades. Pap smear screening and HPV vaccination are powerful tools to prevent cervical cancer. We evaluated the utilization of these tools among AI/ANs living in the Pacific Northwest (PNW).METHODS: The Indian Health Service (IHS) National Data Warehouse's Epi Data Mart was analyzed using all healthcare visits from 2010 to 2020 from IHS, Tribal, and Urban Indian clinics in the PNW. ...
Source: Gynecologic Oncology - November 18, 2022 Category: Cancer & Oncology Authors: A S Bruegl J Emerson K Tirumala Source Type: research
Relationship of political ideology of US federal and state elected officials and key COVID pandemic outcomes following vaccine rollout to adults: April 2021-March 2022
Lancet Reg Health Am. 2022 Dec;16:100384. doi: 10.1016/j.lana.2022.100384. Epub 2022 Oct 31.ABSTRACTBACKGROUND: Scant research, including in the United States, has quantified relationships between the political ideologies of elected representatives and COVID-19 outcomes among their constituents.METHODS: We analyzed observational cross-sectional data on COVID-19 mortality rates (age-standardized) and stress on hospital intensive care unit (ICU) capacity for all 435 US Congressional Districts (CDs) in a period of adult vaccine availability (April 2021-March 2022). Political metrics comprised: (1) ideological scores based on ...
Source: Cancer Control - November 7, 2022 Category: Cancer & Oncology Authors: Nancy Krieger Christian Testa Jarvis T Chen William P Hanage Alecia J McGregor Source Type: research
Weekly Overseas Health IT Links –1st October, 2022.
This article details information required for integration into EHRs to build personalized treatment plans and develop successful SDOH programs that provide resources and support for patients in need. In addition, successful SDOH programs implemented by Kaiser Permanente and Boston Medical Center showcase how supporting clinicians with real-time SDOH data can lead to patient-centric care. Create a 360-Degree Patient View Through TechnologyThe Office of the National Coordinator for Health Information Technology (ONC)indicatesthat the “collection, documentation, reporting, access, and use of SDOH data … can be used t...
Source: Australian Health Information Technology - October 1, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Implementation During a Pandemic: Findings, Successes, and Lessons Learned from Community Grantees
J Cancer Educ. 2022 Sep 3. doi: 10.1007/s13187-022-02213-4. Online ahead of print.ABSTRACTFunding communities through mini-grant programs builds community capacity by fostering leadership among community members, developing expertise in implementing evidence-based practices, and increasing trust in partnerships. The South Carolina Cancer Prevention and Control Research Network (SC-CPCRN) implemented the Community Health Intervention Program (CHIP) mini-grants initiative to address cancer-related health disparities among high-risk populations in rural areas of the state. One community-based organization and one faith-based ...
Source: Cancer Control - September 2, 2022 Category: Cancer & Oncology Authors: Wilhelmenia Mathias Karen A Nichols Jewel Golden-Wright Ciaran M Fairman Tisha M Felder Lauren Workman Karen E Wickersham Kimberly J Flicker Jingxi Sheng Samuel B Noblet Swann Arp Adams Jan M Eberth Sue P Heiney Sara Wilcox James R H ébert Daniela B Frie Source Type: research
Abstracts of Presentations at the Association of Clinical Scientists 143 < sup > rd < /sup > Meeting Louisville, KY May 11-14,2022
Ann Clin Lab Sci. 2022 May;52(3):511-525.ABSTRACT[1] Abraham J. Gitlitz Memorial Lecture: Development of a Broad Spectrum Antiviral-based Intranasal Spray as a Pandemic Preparedness Strategy. Kenneth E. Palmer, Ph. D, Center for Predictive Medicine for Biodefense and Emerging Infectious Diseases and Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY In early 2020, the public health emergency prompted many researchers to contemplate how they might contribute to control of the COVID-19 pandemic. This presentation will detail the research steps taken to bring a novel broad s...
Source: Annals of Clinical and Laboratory Science - July 1, 2022 Category: Laboratory Medicine Source Type: research
